Xiidra®

Lifitegrast ophthalmic solution 5%
ophthalmic solution
Dry Eye/OSD
[ LFA-1 antagonist]
Indication

Indication

Treatment of the signs and symptoms of dry eye disease
Mechanism of Action

Mechanism of Action

Lifitegrast binds to leukocyte cell surface protein LFA-1, reducing T-cell activation and inflammatory cytokine secretion. It’s believed to prevent the formation of an immunologic synapse, inhibit T cell activation, reduce cytokine release, and down-regulate inflammation mediated by T lymphocytes.
Common quantities available

Available Quantities

Cartons of 60 single-use containers (each carton has 12 pouches, with 5 single-use containers)
Dosage

Dosage/Instructions

1 drop in each eye twice daily
Pregnancy & Nursing Data

Pregnancy & Nursing

Teratogenic in rats at high doses. Use cautiously during pregnancy
Pediatric Use

Pediatric Use

≥17 years
Warnings Tab

Contraindications, side effects, etc.

Warnings/Precautions: Inform your doctor if you use other eye drops, wear contact lenses, are pregnant, or breastfeeding. Not approved for use in individuals under 17 years. Common Side Effects: Blurred vision, eye discomfort, eye irritation, unusual or unpleasant taste in the mouth.