Indication
Indicated for steroid-responsive inflammatory conditions with superficial bacterial infection or risk thereof
Mechanism of Action
Aminoglycosides inhibit bacterial protein synthesis. Corticosteroids inhibit arachidonic acid release, reducing inflammation. Extended use may increase risk of glaucoma and cataracts
Available Quantities
2.5 ml, 5 ml, 10 ml
Dosage/Instructions
1 or 2 drops every 4-6 hours, every 2 hours for the first 24 or 48 hours if needed, then taper
Pregnancy & Nursing
Ocular administration of 0.1% dexamethasone is teratogenic in rabbits. Caution advised in severe or unresponsive keratitis as steroids can exacerbate many nonbacterial infections
Pediatric Use
≥2 years
≥2 years≥2 years≥2 years≥2 years≥2 years≥2 years≥2 years≥2 years≥2 years≥2 years
Contraindications, side effects, etc.
Contraindicated in most viral diseases of the cornea and conjunctiva, mycobacterial infection, and fungal diseases of ocular structures. May cause increased intraocular pressure, cataract formation, delayed healing, and secondary ocular infections.
