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Prescribing Alaway®, Zaditor®
Indication
allergic conjunctivitis
Mechanism of Action
Ketotifen antagonizes H1 histamine receptors, stabilizes mast cells, inhibits the release of pro-inflammatorymediators.
Available Quantities
5ml, 10ml
Dosage/Instructions
Adults and children 3 years and older: put 1 drop in the affected eye(s) twice daily, every 8-12 hours, no more than twice per daySafety Info for Alaway®, Zaditor®
Pregnancy & Nursing
Animal studies of toxic doses did not reveal evidence of teratogenecity. No human data is available.
Pediatric Use
≥3 years
Contraindications, side effects, etc.
Contraindications: Avoid if allergic to ketotifen or have eye irritation from contact lenses. Side Effects: More common side effects include eye redness and swelling, headaches, stuffy or runny nose, burning or stinging of eyes, dry eyes, eyelid disorder, eye sensitivity to light, fever, tiredness, achiness, sore throat, pupil enlargement, tearing. Serious side effects can include severe burning, stinging, or irritation after use.ketotifen 0.025%, 0.035%ophthalmic solution - Allergy
Prescribing Alocril®
Indication
allergic conjunctivitisMechanism of Action
Nedocromil inhibits the activation and release of inflammatory mediators such as histamine, prostaglandin D2, and leukotrienes c4 from different types of cellsAvailable Quantities
5mlDosage/Instructions
1 or 2 drops in each eye twice a day at regular intervalsSafety Info for Alocril®
Pregnancy & Nursing
Use during pregnancy only if clearly needed. Unknown if excreted into human milkPediatric Use
≥3 yearsContraindications, side effects, etc.
Warnings: Avoid contact with soft contact lenses. Not approved for use in children younger than 3 years old. Side Effects: Common side effects include headache, runny or stuffy nose, eye redness, increased sensitivity to light, and mild eye irritation. Serious effects may include severe burning, stinging, or irritation after use. For more details, visit Alocril® on Drugs.com.nedocromil sodium 2.0%ophthalmic solution - Allergy
Prescribing Alomide®
Indication
vernal keratoconjunctivitis, vernal conjunctivitis, vernal keratitis.Mechanism of Action
Lodoxamide tromethamine 0.1% (Alomide) stabilizes mast cells by preventing calcium influx upon antigen stimulation and decreasing vascular permeability. It inhibits theType 1 immediate hypersensitivity reaction.Available Quantities
10mlDosage/Instructions
1-2 drops in affected eye four times daily for up to 3 monthsSafety Info for Alomide®
Pregnancy & Nursing
Reproduction studies with lodoxamide tromethamine administered orally to rats and rabbits have not shown any effects of the product on fertility or reproductive performance, or any evidence of embryotoxicity or pre – and post -natal toxicity. However, there are no adequate and well controlled studies in pregnant women. Since animal reproductive studies are not always predictive of human response, ALOMIDE should be used during pregnancy only if clearly neededPediatric Use
>2 yearsContraindications, side effects, etc.
Contraindicated in patients with hypersensitivity to lodoxamide or any other ingredient in the product. Potential side effects include eye irritation, discomfort, or blurred vision.lodoxamide tromethamine 0.1%ophthalmic solution - Allergy, Steroid
Prescribing Alrex®
Indication
Seasonal allergic conjunctivitisMechanism of Action
Inhibits leukocyte migration, capillary dilation, fibroblast proliferationAvailable Quantities
5ml, 10mlDosage/Instructions
1 drop 4 times/daySafety Info for Alrex®
Pregnancy & Nursing
Embryotoxic in rabbits at high doses; no human dataPediatric Use
≥18 yearsContraindications, side effects, etc.
Contraindications: Hypersensitivity to loteprednol etabonate or related corticosteroids. Contraindicated in patients with fungal or viral eye infections. Warnings: Loteprednol etabonate is a corticosteroid and may increase the risk of elevated intraocular pressure, cataracts, and secondary eye infections. It should be used cautiously and under supervision. Common Side Effects: Common side effects include eye irritation, burning, and stinging.Loteprednol Etabonate 0.2%ophthalmic suspension - Allergy
Prescribing Bepreve®
Indication
allergic conjunctivitisMechanism of Action
Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor. It belongs to the second-generation piperidine chemical class. It stabilizes mast cells and suppresses the migration of eosinophils into inflamed tissues.Available Quantities
5, 10mlDosage/Instructions
Instill 1 drop into the affected eye(s) twice a daySafety Info for Bepreve®
Pregnancy & Nursing
No controlled data in human pregnancy. The effects in nursing infants are unknownPediatric Use
≥2 yearsContraindications, side effects, etc.
Warnings: Caution advised for patients with known hypersensitivity to bepotastine. Side Effects: Common side effects include mild taste in mouth, headaches, and temporary eye burning or stinging. Less common side effects are red, sore eyes, body rash, itching, and swelling of the lips, tongue, or throat.bepotastine besilate 1.5%ophthalmic solution - Allergy
Prescribing Crolom®
Indication
vernal keratoconjunctivitis, vernal conjunctivitis, vernal keratitisMechanism of Action
Cromolyn Sodium is a mast cell stabilizer that inhibits mast cell degranulation, thereby preventing the release of histamine and slow-reacting substance of anaphylaxis (SRS-A), which are mediators of type I allergic reactions.Available Quantities
10, 15mlDosage/Instructions
Instill 1 or 2 drops into each eye four to six times daily.Safety Info for Crolom®
Pregnancy & Nursing
Adverse fetal effects (increased resorption and decreased fetal weight) were noted only at the very high parenteral doses that produced maternal toxicity. There are, however, no adequate and well-controlled studies in pregnant women. It is not known whether this drug is excreted in human milkPediatric Use
≥4 yearsContraindications, side effects, etc.
Warnings: Use with caution in patients with known hypersensitivity to cromolyn sodium or any other component of the product. Side Effects: More common side effects include mild and temporary burning or stinging of the eye. Less common or rare side effects include dryness or puffiness around the eye, increased watering or itching of the eye, rash or redness around the eyes, swelling of the membrane covering the white part of the eye, redness of the white part of the eye, styes, or other eye irritation not present before therapy.cromolyn sodium 4.0%ophthalmic solution - Allergy
Prescribing Elestat®
Indication
allergic conjunctivitisMechanism of Action
Epinastine is a second generation antihistamine that also possesses mast cell stabilizing activity. It is a highly selective histamine H1 antagonist and inhibits the release of histamine from mast cells.Available Quantities
5mlDosage/Instructions
Instill 1 drop into each eye twice daily.Safety Info for Elestat®
Pregnancy & Nursing
Epinastine reduced rat pup body weight gain following an oral dose to pregnant rats that was approximately 90,000 times the MROHD. There are, however, no adequate and well-controlled studies in pregnant women. It is not known whether this drug is excreted in human milk.Pediatric Use
≥3 yearsContraindications, side effects, etc.
Contraindications: Should not be used if allergic to epinastine, with bacterial, viral, or fungal infection in the eye without an anti-infective medicine, or in children younger than 2 years without medical advice. Warnings: Avoid use while wearing contact lenses; wait at least 15 minutes after using Elestat before putting in contact lenses. Do not let the dropper tip touch any surface to avoid contamination. Side Effects: Common side effects include burning sensation in the eye, increased blood flow to the whites of the eyes, redness, itching, pain, swelling, or other irritation of the eye. Other side effects may include body aches, chills, cough, difficulty with breathing, ear congestion, fever, headache, loss of voice, nasal congestion, runny nose, sneezing, sore throat, and unusual tiredness or weakness.epinastine HCL 0.05%ophthalmic solution - Allergy, Steroid
Prescribing Inflamase Forte®
Indication
Allergic conjunctivitis, superficial punctate keratitis, iritis, cyclitisMechanism of Action
Inhibits phospholipase A2, reducing prostaglandin synthesisAvailable Quantities
5ml, 10ml, 15mlDosage/Instructions
Varies; up to every hour during the day and every two hours at night as initial therapySafety Info for Inflamase Forte®
Pregnancy & Nursing
Animal reproductive studies not conductedPediatric Use
No studiesContraindications, side effects, etc.
Contraindications: Hypersensitivity to prednisolone or related corticosteroids. Contraindicated in patients with untreated bacterial, fungal, or viral eye infections. Warnings: Prednisolone sodium phosphate is a corticosteroid and may increase the risk of elevated intraocular pressure, cataract formation, and secondary eye infections. It should be used cautiously and under supervision. Common Side Effects: Common side effects include increased eye pressure, eye discomfort, and transient blurred vision.Prednisolone Sodium Phosphate 1.0%ophthalmic solution - Allergy
Prescribing Lastacaft®
Indication
allergic conjunctivitisMechanism of Action
Alcaftadine is a H1 histamine receptor antagonist and inhibitor of the release of histamine from mast cells. Decreased chemotaxis and inhibition of eosinophil activation has also been demonstrated.Available Quantities
3mlDosage/Instructions
Instill 1 drop into each eye once a daySafety Info for Lastacaft®
Pregnancy & Nursing
No adequate and well-controlled studies in pregnant women. It is not known whether this drug is excreted in human milkPediatric Use
≥2 yearsContraindications, side effects, etc.
Contraindications: Should not be used if allergic to alcaftadine or in children younger than 2 years old. Not recommended for treating eye irritation caused by contact lenses. Warnings: Avoid use while wearing contact lenses; wait at least 10 minutes after using Lastacaft before putting in contact lenses. Do not let the dropper tip touch any surface to avoid contamination. Side Effects: Common side effects include mild burning, stinging, or irritation; eye redness or itching; runny or stuffy nose, sore throat, flu symptoms; headache. Serious side effects may include changes in vision, eye pain, increased eye redness, itching of the eye that worsens or lasts for more than 72 hours.alcaftadine 0.25%ophthalmic solution - Allergy
Prescribing Opcon-A®, Naphcon-A®, Visine-A®
Indication
allergic conjunctivitisMechanism of Action
Naphazoline is a sympathomimetic amine that acts as a vasoconstrictor, reducing redness in the eye. Pheniramine is an antihistamine that blocks the effects of histamine, reducing itching and watering of the eyesAvailable Quantities
0.5 fl. oz.Dosage/Instructions
Adults and children 6 years and older: put 1 drop in the affected eye(s) up to 4 times dailySafety Info for Opcon-A®, Naphcon-A®, Visine-A®
Pregnancy & Nursing
No adequate and well-controlled studies in pregnant women. It is not known whether this drug is excreted in human milkPediatric Use
≥6 yearsContraindications, side effects, etc.
Warnings: Not to be used by individuals allergic to naphazoline or pheniramine. Exercise caution if you have heart disease, high blood pressure, urination problems, or narrow-angle glaucoma. Not recommended during pregnancy or breastfeeding without a doctor’s advice. Should not be used in children under 6 years old without doctor’s advice. Avoid prolonged use as it may worsen symptoms and damage blood vessels in the eyes. Side Effects: Common side effects include mild burning or stinging of the eye, dilated pupils, blurred vision, and increased sensitivity to light. Serious side effects can include ongoing or worsening eye redness, eye pain, and changes in vision.naphazoline 0.025% pheniramine 0.3%ophthalmic solution - Allergy
Prescribing Optivar®
Indication
allergic conjunctivitisMechanism of Action
Azelastine is a potent, second-generation, selective, histamine antagonist (histamine-H1-receptor antagonist) used in the treatment of allergic rhinitis and allergic conjunctivitis. It inhibits the release of histamines from mast cells.Available Quantities
6mlDosage/Instructions
Adults and children 3 years and older: put 1 drop in the affected eye(s) twice daily, every 8-12 hours, no more than twice per daySafety Info for Optivar®
Pregnancy & Nursing
Animal studies of toxic doses did not reveal evidence of teratogenicity. No human data is available. It is not known whether this drug is excreted in human milk.Pediatric Use
≥3 yearsContraindications, side effects, etc.
Contraindications: Should not be used if allergic to azelastine. Not to be used in children younger than 3 years old. Warnings: Avoid use while wearing soft contact lenses; wait at least 10 minutes after using Optivar before putting in contact lenses. Do not let the dropper tip touch any surface to avoid contamination. Side Effects: Common side effects include bitter taste in mouth, headaches, and temporary eye burning or stinging. Less common side effects include burning, dry or itching eyes, temporary blurred vision, chills, diarrhea, eye discharge or excessive tearing, fever, general feeling of discomfort or illness, hoarseness or other voice changes, itching skin, joint pain, loss of appetite, muscle aches and pains, nausea, redness, pain, swelling of eye, eyelid, or inner lining of eyelid, runny nose, shivering, sneezing, sore throat, stuffy nose, sweating, tender, swollen glands in neck, trouble in swallowing, trouble sleeping, unusual tiredness or weakness, vomiting.azelastine HCL 0.05%ophthalmic solution - Allergy
Prescribing Pataday Extra Strength Once Daily Relief®
Indication
allergic conjunctivitisMechanism of Action
Olopatadine is a selective histamine H1 antagonist and an inhibitor of the release of histamines from mast cells. It also inhibits the release of other mediators involved in the allergic response, such as eosinophils and neutrophilsAvailable Quantities
Dosage/Instructions
Adults and children 2 years and older: put 1 drop in the affected eye(s) once dailySafety Info for Pataday Extra Strength Once Daily Relief®
Pregnancy & Nursing
Animal studies of toxic doses did not reveal evidence of teratogenicity. No human data is available. It is not known whether this drug is excreted in human milkPediatric Use
≥2 yearsContraindications, side effects, etc.
Warnings: Not approved for use by individuals younger than 2 years old. Do not use while wearing soft contact lenses. A preservative in this medicine could permanently stain the lenses. Use the medicine at least 15 minutes before inserting your contact lenses. Side Effects: Common side effects include headache, runny or stuffy nose, and sore throat. Less common effects are back pain, body or muscle aches, change in taste, chills, cough, diarrhea, feeling of something in the eye, general discomfort, increased cough, loss of strength, loss of appetite, nausea, pain or tenderness around the eyes and cheekbones, redness of the eye or inside of the eyelid, sensitivity of the eyes to light, shivering, sneezing, sweating, swollen glands in the neck, trouble sleeping, trouble swallowing, unusual tiredness or weakness, and voice changes. Serious side effects may include blurred vision, burning, dryness, stinging of the eye, eye redness, irritation, or pain, swelling of the eyelid, face, lips, or feet, and trouble breathing.olopatadine HCL 0.7%ophthalmic solution - Allergy
Prescribing Pataday Once Daily Relief®
Indication
allergic conjunctivitisMechanism of Action
Olopatadine is a selective histamine H1 antagonist and an inhibitor of the release of histamines from mast cells. It also inhibits the release of other mediators involved in the allergic response, such as eosinophils and neutrophilsAvailable Quantities
2.5mlDosage/Instructions
Adults and children 3 years and older: put 1 drop in the affected eye(s) once dailySafety Info for Pataday Once Daily Relief®
Pregnancy & Nursing
Animal studies of toxic doses did not reveal evidence of teratogenicity. No human data is available. It is not known whether this drug is excreted in human milkPediatric Use
≥3 yearsContraindications, side effects, etc.
Warnings: Not approved for use by individuals younger than 2 years old. Do not use while wearing soft contact lenses. A preservative in this medicine could permanently stain the lenses. Use the medicine at least 15 minutes before inserting your contact lenses. Side Effects: Common side effects include headache, runny or stuffy nose, and sore throat. Less common effects are back pain, body or muscle aches, change in taste, chills, cough, diarrhea, feeling of something in the eye, general discomfort, increased cough, loss of strength, loss of appetite, nausea, pain or tenderness around the eyes and cheekbones, redness of the eye or inside of the eyelid, sensitivity of the eyes to light, shivering, sneezing, sweating, swollen glands in the neck, trouble sleeping, trouble swallowing, unusual tiredness or weakness, and voice changes. Serious side effects may include blurred vision, burning, dryness, stinging of the eye, eye redness, irritation, or pain, swelling of the eyelid, face, lips, or feet, and trouble breathing.olopatadine HCL 0.2%ophthalmic solution - Allergy
Prescribing Pataday Twice Daily Relief®
Indication
allergic conjunctivitisMechanism of Action
Olopatadine is a selective histamine H1 antagonist and an inhibitor of the release of histamines from mast cells. It also inhibits the release of other mediators involved in the allergic response, such as eosinophils and neutrophilsAvailable Quantities
5 mlDosage/Instructions
Adults and children 3 years and older: put 1 drop in the affected eye(s) twice daily, every 8-12 hours, no more than twice per daySafety Info for Pataday Twice Daily Relief®
Pregnancy & Nursing
Animal studies of toxic doses did not reveal evidence of teratogenicity. No human data is available. It is not known whether this drug is excreted in human milkPediatric Use
≥3 yearsContraindications, side effects, etc.
Warnings: Not approved for use by individuals younger than 2 years old. Do not use while wearing soft contact lenses. A preservative in this medicine could permanently stain the lenses. Use the medicine at least 15 minutes before inserting your contact lenses. Side Effects: Common side effects include headache, runny or stuffy nose, and sore throat. Less common effects are back pain, body or muscle aches, change in taste, chills, cough, diarrhea, feeling of something in the eye, general discomfort, increased cough, loss of strength, loss of appetite, nausea, pain or tenderness around the eyes and cheekbones, redness of the eye or inside of the eyelid, sensitivity of the eyes to light, shivering, sneezing, sweating, swollen glands in the neck, trouble sleeping, trouble swallowing, unusual tiredness or weakness, and voice changes. Serious side effects may include blurred vision, burning, dryness, stinging of the eye, eye redness, irritation, or pain, swelling of the eyelid, face, lips, or feet, and trouble breathing.olopatadine HCL 0.1%ophthalmic solution - Allergy
Prescribing Verkazia®
Indication
vernal keratoconjunctivitisMechanism of Action
Blocks the release of pro-inflammatory cytokines such as IL-2; exact mechanism in VKC treatment not fully understoodAvailable Quantities
120 single-dose vials (0.3 mL each)Dosage/Instructions
Instill 1 drop into each affected eye 4 times daily (morning, noon, afternoon, and evening)Safety Info for Verkazia®
Pregnancy & Nursing
No adequate and well-controlled studies in pregnant women. Oral administration in animals did not produce teratogenicity at clinically relevant dosesPediatric Use
≥4 yearsContraindications, side effects, etc.
Warnings: Not enough studies have been performed to establish the safety and efficacy of Verkazia® in the elderly. The risks and benefits should be considered when using this medication during breastfeeding. Side Effects: Common side effects include burning, pain, itching, or discomfort of the eye, redness of the white part of your eyes or inside of your eyelids, and pain upon instillation of drops. Less common side effects include blurred vision, clear or yellow fluid from the eye, difficulty with reading, eye irritation, feeling of having something in the eye, halos around lights, headache, itching skin, redness, swelling, or itching of the eyelid, sticky or matted eyelashes, stinging, and watery eye. Serious side effects may include bladder pain, bloody or cloudy urine, body aches or pain, chills, cough, difficult, burning, or painful urination, ear congestion, fever, headache, loss of voice, lower back or side pain, runny or stuffy nose, sneezing, sore throat, trouble breathing, and unusual tiredness or weakness.Cyclosporine Ophthalmic Emulsion 0.1%ophthalmic emulsion - Allergy
Prescribing Zerviate®
Indication
allergic conjunctivitisMechanism of Action
Cetirizine, a second-generation antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria1Available Quantities
5ml, 7.5ml, 30-ct 0.2 mL dropperettesDosage/Instructions
Adults and children 2 years and older: put 1 drop in the affected eye(s) twice dailySafety Info for Zerviate®
Pregnancy & Nursing
Animal studies of toxic doses did not reveal evidence of teratogenicity. No human data is available. It is not known whether this drug is excreted in human milkPediatric Use
≥2 yearsContraindications, side effects, etc.
Warnings: Zerviate is for use in adults and children at least 2 years old and is not for use in treating eye irritation caused by wearing contact lenses. Side Effects: Common side effects may include eye pain after inserting the eye drops, eye redness, and decreased vision. It’s important to seek emergency medical help if signs of an allergic reaction occur, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.cetirizine 0.24%ophthalmic solution
