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AzaSite®

azithromycin 1%
ophthalmic solution
Antibiotic
[ macrolide antibiotic]
Indication

Indication

bacterial conjunctivitis, blepharitis*
Mechanism of Action

Mechanism of Action

Azithromycin is a macrolide antibiotic that works by binding to the 23S rRNA of the 50S ribosomal subunit of the bacteria, inhibiting protein synthesis and therefore bacterial growth. Macrolides, including azithromycin, have a broad-spectrum antibacterial activity due to their strong affinity for bacterial ribosomes. Effective against the following organisms: CDC coryneform group G, Haemophilus influenzae, Staphylococcus aureus, Streptococcus mitis group, Streptococcus pneumoniae
Common quantities available

Available Quantities

2.5 ml
Dosage

Dosage/Instructions

Day 1-2: Instill 1 drop in the affected eye(s) 2x/day Days 3-7: Instill 1 drop in the affected eye(s)1x/day
Pregnancy & Nursing Data

Pregnancy & Nursing

Animal studies with doses up to 200 mg/kg/day, approximately 5,000 times the maximum human ocular daily dose of 2 mg, showed no harm to the fetus but caused moderate maternal toxicity. However, there are no adequate and well-controlled studies in pregnant women. It is not known whether azithromycin is excreted in human milk.
Pediatric Use

Pediatric Use

≥1 year
Warnings Tab

Contraindications, side effects, etc.

Contraindications: Allergy to azithromycin. Warnings: Not for injection, only for topical ophthalmic use. Common Side Effects: Eye irritation, blurred vision, nasal congestion, periocular swelling, rash, sinusitis, urticaria.