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Azopt®

Brinzolamide 1%
ophthalmic suspension
Antiglaucoma
[ Carbonic Anhydrase Inhibitor]
Indication

Indication

Lowering intraocular pressure in ocular hypertension or open-angle glaucoma
Mechanism of Action

Mechanism of Action

Brinzolamide inhibits carbonic anhydrase II in the ciliary processes, which is believed to slow the formation of bicarbonate ions. This reduction leads to decreased sodium and fluid transport, subsequently lowering aqueous humor secretion and reducing intraocular pressure.
Common quantities available

Available Quantities

10 ml, 15 ml
Dosage

Dosage/Instructions

1 drop 3 times daily
Pregnancy & Nursing Data

Pregnancy & Nursing

There are no adequate and well-controlled studies in pregnant women. Use cautiously during pregnancy.
Pediatric Use

Pediatric Use

No studies
Warnings Tab

Contraindications, side effects, etc.

Contraindicated in patients with hypersensitivity to brinzolamide or any other component. Warnings include sulfonamide hypersensitivity reactions, temporary blurred vision, avoiding contamination of the product, caution in patients with intercurrent ocular conditions, and concomitant topical ocular therapy. The preservative in Azopt, benzalkonium chloride, may be absorbed by soft contact lenses, so lenses should be removed during instillation and reinserted after 15 minutes.