Eye Know O.D. logo
Register
Email Address: *
First Name: *
Last Name: *
Title:
Profession:
Password: *
Confirm Password: *

By clicking “Register” you are agreeing to the Terms and Conditions and Privacy Policy.

Betagan®

Levobunolol HCL (0.25%, 0.5%)
ophthalmic solution
Antiglaucoma
[ Beta Blocker]
Indication

Indication

Lowering IOP in chronic open-angle glaucoma or ocular hypertension
Mechanism of Action

Mechanism of Action

Levobunolol is a noncardioselective beta-blocker. It lowers intraocular pressure (IOP) by decreasing aqueous humor production. This is achieved through the inhibition of beta-adrenergic receptors in the ciliary body, reducing cAMP levels and subsequently decreasing aqueous humor formation.
Common quantities available

Available Quantities

5 ml, 10 ml, 15 ml
Dosage

Dosage/Instructions

0.5%: 1 or 2 drops in the morning to start, twice daily maximum. 0.25%: 1 or 2 drops twice daily.
Pregnancy & Nursing Data

Pregnancy & Nursing

Use cautiously during pregnancy. No adequate and well-controlled studies in pregnant women.
Pediatric Use

Pediatric Use

No studies
Warnings Tab

Contraindications, side effects, etc.

Contraindicated in asthma, severe COPD, sinus bradycardia, AV block, cardiac failure, cardiogenic shock, hypersensitivity. Warnings include systemic absorption risks, cardiac failure, vascular insufficiency, obstructive pulmonary disease, diabetes mellitus, thyrotoxicosis, choroidal detachment. Adverse reactions: ocular burning, stinging, blepharoconjunctivitis, heart rate and blood pressure decrease, iridocyclitis, headache, ataxia, dizziness, lethargy, urticaria, pruritus.