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Blephamide® Ointment

sulfacetamide 10%, prednisolone acetate 0.2%
ophthalmic ointment
Antibiotic/Steroid
[ sulfonamide antibiotic, corticosteroid]
Indication

Indication

ocular surface inflammation with superficial bacterial infection or risk of infection
Mechanism of Action

Mechanism of Action

Sulfacetamide sodium inhibits bacterial folic acid synthesis, crucial for bacterial growth. Prednisolone acetate is a corticosteroid, reducing inflammation by suppressing leukocyte migration and capillary permeability.
Common quantities available

Available Quantities

3.5 gm tube
Dosage

Dosage/Instructions

Apply 1/2 inch ribbon to affected eye(s) every 3-4 times per day.
Pregnancy & Nursing Data

Pregnancy & Nursing

Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Pediatric Use

Pediatric Use

≥6 years
Warnings Tab

Contraindications, side effects, etc.

Contraindications: Allergy to sulfacetamide sodium, prednisolone, or any part of Blephamide; fungal, TB, or viral infection of the eye. Warnings: Caution if breastfeeding; long-term use may increase risk of cataracts or glaucoma. Side Effects: Common side effects include eye irritation, dizziness. Serious side effects include allergic reactions, changes in eyesight, severe eye irritation, sensitivity to light, rare severe reactions to sulfa drug