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Diclocil®

Dicloxacillin
oral capsule
Antibiotic
[ Penicillinase-Resistant Penicillin]
Indication

Indication

Treatment of infections caused by penicillinase-producing staphylococci, such as preseptal cellulitis
Mechanism of Action

Mechanism of Action

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to cell lysis and death
Common quantities available

Available Quantities

250 mg, 500 mg capsules
Dosage

Dosage/Instructions

Adults: 250 to 500 mg every 6 hours. Children under 40 kg: 12.5 to 25 mg/kg/day in divided doses every 6 hours
Pregnancy & Nursing Data

Pregnancy & Nursing

No evidence of risk in humans but studies inadequate. Generally considered safe in pregnancy. Caution should be exercised when administered to a nursing woman
Pediatric Use

Pediatric Use

≥1 year
Warnings Tab

Contraindications, side effects, etc.

Contraindications: Hypersensitivity to dicloxacillin, penicillins, or any component of the formulation. Warnings/Precautions: Use with caution in patients with a history of severe allergic reactions to other beta-lactams. Monitor renal function in patients with renal impairment. Common Side Effects: Nausea, vomiting, diarrhea, allergic reactions (rash, hives), and rarely, interstitial nephritis, Stevens-Johnson syndrome, and Clostridium difficile-associated diarrhea.