Dilaudid®
Hydromorphone Hydrochloride
oral solution, oral tablet

Indication
Management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Can be used for severe post-operative pain following ocular surgery

Mechanism of Action
Hydromorphone is an opioid agonist and works by changing the way the brain and nervous system respond to pain

Available Quantities
Tablets: 2 mg, 4 mg, 8 mg; Oral Solution: 5 mg/5 mL

Dosage/Instructions
Dosage individualized; use lowest effective dosage for shortest duration consistent with individual patient treatment goals

Pregnancy & Nursing
Use during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated. Caution should be exercised when administered to a nursing woman

Pediatric Use
≥2 years

Contraindications, side effects, etc.
Contraindications: Avoid in patients with gastrointestinal blockage, paralytic ileus, or recent use of MAO inhibitors (within 14 days).
Warnings/Precautions: Monitor for respiratory depression, particularly in elderly or debilitated patients. Be cautious in patients with a history of head injury, seizures, drug or alcohol addiction, or mental illness. Risk of serotonin syndrome when combined with certain medications. Not recommended for pregnant or breastfeeding women due to the risk of dependency in the newborn and potential harm to the nursing baby.
Common Side Effects: May include constipation, nausea, vomiting, dizziness, drowsiness, headache, mood changes, itching, dry mouth, and flushing.