Fortified Vancomycin

Vancomycin 50 mg/ml
ophthalmic solution
Antibiotic
[ Glycopeptide Antibiotic]
Indication

Indication

Corneal ulcer
Mechanism of Action

Mechanism of Action

Inhibits bacterial cell wall synthesis, effective against Gram-positive bacteria including MRSA.
Common quantities available

Available Quantities

Varies (compounded)
Dosage

Dosage/Instructions

Sight-threatening ulcers: 1 drop every 5 minutes for five doses, then 1 drop every 30 to 60 minutes around-the-clock. Compounding Instructions: Reconsitute 500 mg of vancomycin powder with sterile water to form a 10 ml solution. Keep refrigerated and discard after 7 days.
Pregnancy & Nursing Data

Pregnancy & Nursing

Limited data; use with caution in pregnancy and nursing
Pediatric Use

Pediatric Use

≥1 week
Warnings Tab

Contraindications, side effects, etc.

Contraindications: Allergy to corn or corn products (if solution is dextrose based). Warnings: Caution in congestive heart failure, hearing loss, kidney disease. Common Side Effects: Nausea, abdominal pain, hypokalemia, dermatologic issues like exanthema, pruritus, infusion reaction, renal issues like increased serum creatinine, nephrotoxicity, and other effects like fatigue, mucosal inflammation, pyrexia​​​​​​.