Fortified Voriconazole
Voriconazole 0.5 mg/mL
ophthalmic solution
Antifungal
[ Azole Antifungal]
Indication
Fungal keratitis, fungal conjunctivitis
Mechanism of Action
Inhibits fungal cytochrome P450 enzymes, preventing the synthesis of ergosterol, a key component of the fungal cell membrane. Effective against a wide range of yeasts and filamentous fungi.
Available Quantities
20 ml
Dosage/Instructions
1 drop in affected eye(s) every hour, around the clock.
Compounding Instructions: Mix 1 ml of intravenous voriconazole (concentration: 10mg/mL) with 19 ml of sterile water. Filter the mixture before use. Discard within 7 days.
Pregnancy & Nursing
Use with caution in pregnancy and nursing; teratogenic in animal studies
Pediatric Use
≥2 years
Contraindications, side effects, etc.
Contraindications: Galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption. Precautions: Caution while driving, especially at night; discuss heart, liver, kidney issues with doctor. Common Side Effects: Headache, visual disturbances, nausea, vomiting, dizziness, flushing. Serious Side Effects: Fever, chills, fast heartbeat, confusion, unusual bruising/bleeding, liver issues, hallucinations, chest pain, rash, difficulty breathing, swelling, increased sensitivity to sunlight. Storage and Disposal: Store tablets at room temperature; store oral suspension in the refrigerator before mixing and at room temperature after mixing. Dispose of unused medication properly.