Ilevro®

Nepafenac Suspension 0.3%
ophthalmic suspension
NSAID
[ Nonsteroidal Anti-inflammatory Drug]
Indication

Indication

Treatment of pain and inflammation associated with cataract surgery
Mechanism of Action

Mechanism of Action

After topical ocular dosing, nepafenac penetrates the cornea and is converted by ocular tissue hydrolases to amfenac, which inhibits prostaglandin synthesis by blocking cyclooxygenase (COX)
Common quantities available

Available Quantities

1.7ml, 3ml
Dosage

Dosage/Instructions

1 drop daily beginning 1 day before cataract surgery, on the day of surgery, an additional drop 30 to 120 minutes prior to surgery, and continue for 2 weeks
Pregnancy & Nursing Data

Pregnancy & Nursing

Pregnancy Category C; not recommended during late pregnancy due to effects on the fetal cardiovascular system. Not known if excreted in human milk
Pediatric Use

Pediatric Use

≥10 years
Warnings Tab

Contraindications, side effects, etc.

Contraindications: Hypersensitivity to nepafenac or related NSAIDs. It is contraindicated in patients with a history of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs. Warnings: Nepafenac can cause eye irritation and burning upon instillation. It may also increase the risk of ocular complications and should be used cautiously in certain eye conditions. Common Side Effects: Common side effects include eye irritation, stinging or burning sensation, eye redness, and blurred vision.