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Ultracet®

Tramadol and Acetaminophen
oral tablet
Analgesics & Anesthetics
[ Opioid Analgesic (Tramadol), Aniline Analgesic (Acetaminophen)]
Indication

Indication

Short-term (five days or less) management of acute pain
Mechanism of Action

Mechanism of Action

Tramadol is a centrally acting synthetic opioid analgesic that binds to mu-opioid receptors and inhibits the reuptake of norepinephrine and serotonin, which may contribute to its analgesic effects. Acetaminophen is a non-opioid, non-salicylate analgesic and antipyretic. It works by inhibiting the synthesis of prostaglandins in the central nervous system and peripherally blocking pain impulse generation, producing antipyresis from inhibition of the hypothalamic heat-regulating center
Common quantities available

Available Quantities

37.5mg tramadol and 325mg acetaminophen
Dosage

Dosage/Instructions

2 tablets every 4 to 6 hours as needed for pain relief up to a maximum of 8 tablets per day
Pregnancy & Nursing Data

Pregnancy & Nursing

Use during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated. Caution should be exercised when administered to a nursing woman
Pediatric Use

Pediatric Use

≥12 years
Warnings Tab

Contraindications, side effects, etc.

Contraindications: Allergies to tramadol or acetaminophen, severe respiratory issues, drug dependence, concurrent use of MAOIs, and gastrointestinal blockage. Warnings/Precautions: Doctors should be aware of potential addiction risks, respiratory depression, and the need for liver function monitoring. Patients with a history of seizures or those at risk should be closely monitored. Be cautious about potential serotonin syndrome when used with other serotonin-increasing medications. Common Side Effects: Nausea, dizziness, constipation, headache, and drowsiness are common side effects of Ultracet.