Verkazia®
Cyclosporine Ophthalmic Emulsion 0.1%
ophthalmic emulsion
Allergy
[ Calcineurin Inhibitor Immunosuppressant]
Indication
vernal keratoconjunctivitis
Mechanism of Action
Blocks the release of pro-inflammatory cytokines such as IL-2; exact mechanism in VKC treatment not fully understood
Available Quantities
120 single-dose vials (0.3 mL each)
Dosage/Instructions
Instill 1 drop into each affected eye 4 times daily (morning, noon, afternoon, and evening)
Pregnancy & Nursing
No adequate and well-controlled studies in pregnant women. Oral administration in animals did not produce teratogenicity at clinically relevant doses
Pediatric Use
≥4 years
Contraindications, side effects, etc.
Warnings: Not enough studies have been performed to establish the safety and efficacy of Verkazia® in the elderly. The risks and benefits should be considered when using this medication during breastfeeding. Side Effects: Common side effects include burning, pain, itching, or discomfort of the eye, redness of the white part of your eyes or inside of your eyelids, and pain upon instillation of drops. Less common side effects include blurred vision, clear or yellow fluid from the eye, difficulty with reading, eye irritation, feeling of having something in the eye, halos around lights, headache, itching skin, redness, swelling, or itching of the eyelid, sticky or matted eyelashes, stinging, and watery eye. Serious side effects may include bladder pain, bloody or cloudy urine, body aches or pain, chills, cough, difficult, burning, or painful urination, ear congestion, fever, headache, loss of voice, lower back or side pain, runny or stuffy nose, sneezing, sore throat, trouble breathing, and unusual tiredness or weakness.